MSD 3,2 liter standard SUB

Developed in collaboration with MSD

3,2 liter Single-Use-Bioreactor (SUB) developed in collaboration with the BioProcess Development Group at Merck & Co., Inc., 2000 Galloping Hill Road, Kenilworth, NJ 07033 U.S.A. (known as MSD outside the US and Canada).


  • All rigid mono component plastics
  • Magnetic-Bottom-Drive (MBD)
  • 3 free sensor ports PG 13,5
  • 1 sensor ports PG 13,5 installed with PolarWell for non-invasive inserts for polarographic MT DO sensor (pn 4720-220)
  • 1 sensor ports PG 13,5 for optional all polymeric pH Single-Use-Sensor with K9 connector - (pn: 4520-225)
  • Special designed impeller – integrated with magnet motor named Aero
  • L-sparger with 7 x 0,5 mm drilled holes (max sparge gas pressure 500 mBar)
  • 3 x 10 mm baffles extending from head plate
  • 2 x deep tubes with CPC connector for ATF-2 connection
  • 12 small diameter hoses for various inlet and outlet length 600 mm
  • SUB outside dimension OD 137 x H 270 mm = 3,2 liter Vessel Volume (VV)
  • Working Volume (WV) 500 ml will cover sensors, 1.000 ml will cover the impeller

Need to have accessories:

  • Re-usable Stainless Steel gas cooler (pn: 22985) with OD 12 mm inlet and 6 mm outlet
  • One of 3 different size Magnetic-Stirrer-Table (MST) (pn: 2250-S-12(B), pn: 2250-C-8, pn: 2250-U-8(B)
  • If needed - converter kit for servo motor (pn: 2252, pn: 2253, pn: 2254)

Parts manufactured and supplied by CerCell seen from left: one gas cooler in place, many customized gas coolers, MST-U-Compact occupying less space on lab table.

Nice to have accessories

  • Re-Usable-Jacket for liquid heating/cooling fitted to MST (RUJ-MST) (pn: 2286)
  • Electrical-Heating-Blanket 110 or 230 VAC (pn: 22??? series)
  • Sterile-Filter-Heater 110-230 VAC (pn: 2211)
  • SUB-Support-Square (SSS) plate for any of the 3 MST (pn: 2259-137-35)

Seen from left: Packed head plate layout. The final SUB design rendered. At right the highly efficient Aero magnet motor with ceramic bearing and impeller.


  • Three wall baffles of width 10 mm x thickness of 4 mm.
  • Extend from head plate down to 0,5 L, 43 mm from the bottom.
  • Approximate clearance between SUB wall and baffle is 4,5 mm.


  • Aero MBD/ elephant ear impeller, OD 60 mm, 3 blades, 45 degrees clock wise rotation and down flow
  • Impeller mounted 55 mm from the bottom
  • Extensive fluid dynamic analysis performed for minimum shear forces and gradients