PR-SUB (Perfusion-Ready-Single-Use-Bioreactor)

For medium size perfusion systems not integrating a SUB CerCell offer the “LowRider-13” solution. Bottom outlet for connecting a pump (like centrifugal or peristaltic) used for circulating broth through the CFF/HFF in cell retention setup. The "LowRider-10" designed for up to 10 liter Working Volume in perfusion setup.

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LowRider heads

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LowRIder-10 bottom details

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LowRider-10 foam bottle

The LowRider-13 PR-SUB, the unique broth outlet at bottom for a hose connection and a first aseptic connector, retentate return to the SUB through hose, aseptic connector(s) on head plate and back into the LowRider-13 PR-SUB. Here photo 2 and 3 show a specific end-user desired prototype for in-house KLa testing and bottom barb, hose configuration.

Features for the LowRider-13 size PR-SUB:

• Rigid mono component PolyCarbonate
• Vessel dimension: OD 200 x 445 mm = 13 liter Vessel Volume
• Multiple agitation, drive options:

1. Head-Plate-Drive (HPD) for selectable servo motor drive
2. Magnetic-Bottom-Drive (MBD) for selectable servo motor drive via MST

• Multiple impeller’s (and turbine’s) options, such as:

1. Two elephant ear impeller, OD 100 mm, 3 blades, 45 degrees, CW rotation down flow, 55 mm from the bottom, 120 mm between
2. One bottom Rushton OD 100 mm turbine, one OD 90 mm pitch blade impeller, 120 mm separated

Head plate with 10 x PG 13.5 head plate ports pre-installed with:

1. port with non-invasive PolarWell or VisiWell for DO RUS insert
2. port with OneFerm pH Single-Use-Sensor with K9 connector
3. Aeration port with 9 hole L-sparger or ring-sparger macro or your preferred sparger
4. first inlet port for retentate return with 750 mm 9.5 mm hose + your preferred connector (such as AseptiQuick AQS17004 1/4")
5. second inlet port for retentate return with 750 mm 9.5 mm hose + your preferred connector (such as AseptiQuick AQS17004 1/4")
6. Port for harvest via large diameter tube to bottom and external 1,000 mm hose
7. Port for inoculation via tube 60 mm from bottom and external 1,000 mm hose
8. In&Out 1 with 4 all small inner diameter 1,200 mm long weldable closed hoses
   1. 1 x inoculation inlet 30 mm from bottom
   2. 1 x media inlet 30 mm from bottom
   3. 1 x outlet sample 30 mm from bottom
   4. 1 x inlet for acid, NaOH 30 mm under cover
9. In&Out 2 with 2 all small inner diameter
   1. 1 x bottom harvest hose with swabable valve
   2. 1 x acid inlet small inner diameter 1,200 mm long closed weldable hose
   3. 1 x thermo couple well ID 7 mm
10. Exhaust to 500 ml foam collecting bottle, further 1,000 mm hose to 2 x 400 cm2 sterile filters

  11^th port = "LowRider" bottom broth barb outlet with 200 mm long 9.5 x 14.3 mm hose + your preferred connector (such as AseptiQuick AQS17006 3/8")

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LowRider-10 produ 2

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LowRider-10 produ 1

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LowRider-10 produ 1 top

LowRider-13 PR-SUB for HPD drive and electrical heating blanket thermal control. All photos from the same PR-SUB also show the attached foam collecting bottle and plenty of hoses for various connections.

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Accessories to be found here - Accessory Products