“The Flexibility of Small-Scale Single-Use Bioreactor Solutions”
The authors present a case study in which four single-use vessels were fitted to an existing Process-Control-System. Presented 1st of August 2016.
Performed by Christian Müller, Lena Nielsen, Torben P. Frandsen all from www.cmcbio.com
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SUB's 250-1,500 ml Working Volume
CellVessel 21-2000 with circular stator generating radial media mixing cultivating CHO cells on DasGip MP8 Process-Control-System. Test performed at Bioneer A/S, Denmark, senior scientist Holger K. Riemann, www.bioneer.dk. Conclusion is that mass transfer is significant higher allowing cells to grow faster and obtain max density followed by excess lactate concentration.
SUB's 50-200 ml Working Volume
CellVessel 23-0250 inserted in HSF cultivating CHO cells on DasGip MP8 Process-Control-System. Performed by senior scientist Holger K. Riemann, Bioneer A/S, Denmark, www.bioneer.dk.